Scientific References

1. Steward, Louise, “The Alzheimer’s cure that worked on mice”, in Newsweek Europe, August, 6, 2014: http://europe.newsweek.com/alzheimers-cure-worked-mice-compound-tc-2153-263171?rm=eu

2. Kamceva, Marjia and others, “Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function”, in Neural Plasticity, 2016: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844879/

3. Yale News, “In search for Alzheimer’s drug, a major STEP forward”, in Yale News, August, 6, 2014: http://news.yale.edu/2014/08/06/search-alzheimer-s-drug-major-step-forward

4. Johnson, M.A. and Lambroso P.J., “A common STEP in the synaptic pathology of diverse neuropsychiatric disorders”, in Yale Journal of Biology and Medicine, December, 13, 2012: http://www.ncbi.nlm.nih.gov/pubmed/23239949

5. Baum M.L. and others, “A STEP forward in neural function and degeneration”, in Communicative & Integrative Biology, September, 3, 2010: http://www.ncbi.nlm.nih.gov/pubmed/21057629

6. Kulikov A.V. and others, “A new synthetic varacin analogue, 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride (TC-2153), decreased hereditary catalepsy and increased the BDNF gene expression in the hippocampus in mice”, in Psychopharmacology, June, 2012: http://www.ncbi.nlm.nih.gov/pubmed/22127556

7. Xu J. and others, “Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease”, in PLoS Biology, August, 5, 2014: http://www.ncbi.nlm.nih.gov/pubmed/25093460

8. Zhang Y. and others, “Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model”, in Proceedings of the National Academy of Sciences of the United States, November, 2, 2010: http://www.ncbi.nlm.nih.gov/pubmed/20956308

9. Yale University, “Drug reverses brain deficits of Alzheimer's in mouse model” https://www.sciencedaily.com/releases/2014/08/140805150832.htm

10. Martha Snyder Taggart, “Compound Restores Memory Function in Mouse Alzheimer’s Model” https://www.brightfocus.org/alzheimers/news/compound-restores-memory-function-mouse-alzheimers-model

11. Johns Hopkins University, “Chronic Inflammation Linked to Dementia” https://www.alzheimers.net/chronic-inflammation-linked-to-dementia

12. Lycopene attenuates Aβ1-42 secretion and its toxicity in human cell and Caenorhabditis elegans models of Alzheimer disease https://pubmed.ncbi.nlm.nih.gov/26453763/

13. Further evidence that controlling high blood pressure can reduce dementia, Alzheimer's risk https://www.nia.nih.gov/news/further-evidence-controlling-high-blood-pressure-can-reduce-dementia-alzheimers-risk

14. Lentinula edodes-derived polysaccharide rejuvenates mice in terms of immune responses and gut microbiota https://pubmed.ncbi.nlm.nih.gov/26135107/

15. Blood Pressure and Dementia – a Comprehensive Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002634/

16. How the brain's immune system could be harnessed to improve memory https://www.sciencedaily.com/releases/2020/02/200211103731.htm

17. The effects of soursop supplementation on blood pressure, serum uric acid, and kidney function in a prehypertensive population in accordance with the 2017 ACC/AHA guideline https://clinicaltrials.gov/ct2/show/NCT03531203

18. Red Raspberries and Their Bioactive Polyphenols: Cardiometabolic and Neuronal Health Links https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717884/

19. The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915757/

20. Neuroprotective effects of ginsenosides https://pubmed.ncbi.nlm.nih.gov/17265697/

21. Improvement of cognitive deficit in Alzheimer's disease patients by long term treatment with korean red ginseng https://pubmed.ncbi.nlm.nih.gov/23717092/

22. Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838478/

23. Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial https://pubmed.ncbi.nlm.nih.gov/26568249/

24. Evaluation of antioxidant and antiradical properties of Pomegranate (Punica granatum L.) seed and defatted seed extracts https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325071/

25. Alzheimer’s wake-up call https://www.health.harvard.edu/staying-healthy/alzheimers-wake-up-call

26. Lycopene and cognitive function https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558668/

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